NIH Guide - Vol. 20, No. 21 - May 31, 1991

Margaret VanAmringe Direc to r , Center f o r Research Dissemination and Liaison Agency f o r Health Care Pol icy and Research Parklawn Building, Room 18A-10 5600 F i she r s Lane Rockvil le , MD 20857 Telephone: (301) 443-2904 For f i s c a l and admin i s t r a t ive matters, con tac t : Ralph S l o a t Chief,. Grants Management Branch Agency f o r Heal th C a r e Pol icy and Research Parklawn Building, Room 18A27 5600 F i she r s Lane Rockvil le , MD 20857 Telephone: (301) 443-4033 HEALTH SERVICES RESEARCH PRIORITY AREAS FOR ACCELERATED SMALL GRANT APPLICATION REVIEW * I , / PA: PA-91-62 P.T. 34, 42; K . W . 0730050, 0730000 Agency f o r Heal th C a r e Pol icy and Research The Agency f o r Heal th C a r e Pol icy and Research (AHCPR) announces p r i o r i t y areas f o r small g ran t a p p l i c a t i o n s f o r h e a l t h s e r v i c e s r e sea rch , inc luding conferences, pursuant t o T i t l e I X of t h e Publ ic Health Serv ice (PHS) A c t and s e c t i o n 1142 of t h e Soc ia l Secur i ty A c t and i n v i t e s a p p l i c a t i o n s f o r such g r a n t s . Small g ran t a p p l i c a t i o n s are those with t o t a l d i r e c t c o s t s of $50,000 o r less over t h e p r o j e c t per iod . AHCPR is p a r t i c u l a r l y i n t e r e s t e d i n N I H G U I D E Vol. 20, No. 21, May 31, 1991 Page 11 r ece iv ing s m a l l g r an t a p p l i c a t i o n s from ind iv idua l s new t o t h e h e a l t h s e r v i c e s r e sea rch f i e l d . Small g ran t a p p l i c a t i o n s proposing a conference o r r e sea rch i n t h e p r i o r i t y areas i d e n t i f i e d below w i l l be accorded an acce le ra t ed review. This acce le ra t ed review w i l l permit AHCPR t o n o t i f y a p p l i c a n t s of funding dec i s ions approximately s i x months a f te r r e c e i p t of a p p l i c a t i o n s . The information i n t h i s n o t i c e , as w e l l as f u t u r e changes, w i l l be publ ished i n t h e Federal Reg i s t e r . AHCPR is a l s o i s s u i n g a sepa ra t e Federal Reg i s t e r n o t i c e and announcement i n t h e N I H Guide f o r Grants and Cont rac ts with a d d i t i o n a l information p e r t a i n i n g t o a l l conference g ran t proposa ls , inc luding those i n excess of $50,000. Research p r i o r i t y areas, inc luding conferences, t h a t q u a l i f y small g ran t proposa ls f o r acce le ra t ed review are: 1 . Research on h e a l t h care s e r v i c e s f o r underservedl disadvantaged populat ions, e .g . , minori ty h e a l t h i s sues , ru ra l h e a l t h i s sues , methods t o improve access; 2. Research on c o s t s , access, and q u a l i t y of care f o r t h e w uninsured/underinsured; N I H G U I D E Vol. 20, No. 21, May 31, 1991 Page 12 3. Research on h e a l t h care s e r v i c e s f o r i nd iv idua l s with H I V i n f e c t i o n s , inc luding i s s u e s r e l a t e d t o c o s t s , access, and q u a l i t y of care d e l i v e r e d t o such ind iv idua l s ; 4 . Research on medical l i a b i l i t y i s s u e s , e .g : , de te rminants o f , o r a l t e r n a t i v e approaches t o reduce medical l i a b i l i t y ; 5 . Research on c l i n i c a l p rac t i ce -o r i en ted primary care; t h a t desc r ibes t h e n a t u r a l h i s t o r y and t h e management of cond i t ions commonly encountered i n primary care p r a c t i c e ; and 6 . Conferences on t h e areas s p e c i f i e d above as w e l l as o t h e r h e a l t h s e r v i c e s r e sea rch t o p i c s of genera l i n t e r e s t . These p r i o r i t y areas supersede previous ly announced p r i o r i t i e s f o r s m a l l g r a n t a p p l i c a t i o n s . Comments on t h e p r i o r i t i e s are being s o l i c i t e d through t h e Federal Reg i s t e r . Any changes i n p r i o r i t i e s r equ i r ed t o address Nat ional concerns w i l l be announced before becoming e f f e c t i v e . I f t h e a p p l i c a t i o n submit ted i n response t o t h i s RFA is s u b s t a n t i a l l y similar t o a r e sea rch g r a n t a p p l i c a t i o n a l r eady submit ted t o t h e N I H f o r review, bu t has no t y e t been reviewed, t h e a p p l i c a n t w i l l be asked t o withdraw e i t h e r t h e pending a p p l i c a t i o n o r t h e new one. Simultaneous submission of i d e n t i c a l a p p l i c a t i o n s w i l l no t be allowed, nor w i l l e s s e n t i a l l y i d e n t i c a l a p p l i c a t i o n s be reviewed by d i f f e r e n t review committees. Therefore , an a p p l i c a t i o n cannot be submit ted i n response t o t h i s RFA t h a t is e s s e n t i a l l y i d e n t i c a l t o one t h a t has a l r eady been reviewed. This does no t preclude t h e submission of s u b s t a n t i a l r e v i s i o n s of a p p l i c a t i o n s a l r eady reviewed, bu t such a p p l i c a t i o n s must inc lude an in t roduc t ion address ing t h e previous c r i t i q u e . AHCPR urges a p p l i c a n t s t o submit p r i o r i t y cons ide ra t ion small g r a n t a p p l i c a t i o n s t h a t address s p e c i f i c o b j e c t i v e s of t h e pub l i ca t ion "Healthy People 2000." P o t e n t i a l a p p l i c a n t s may o b t a i n a copy of "Healthy People 2000" ( f u l l r e p o r t ; Stock No. 017-001-00474-0) (summary r e p o r t ; Stock No. 017-001-00473-1) through the Superintendent of Documents, Government P r i n t i n g Off ice , Washington, D . C . 20402-9325, te lephone 202-783-3238. SPECIAL INSTRUCTIONS TO APPLICANTS CONCERNING INCLUSION OF WOMEN AND MINORITIES I N RESEARCH STUDY POPULATIONS AHCPR observes N I H and ADAMHA po l i cy r e q u i r i n g a p p l i c a n t s f o r c l i n i c a l r e sea rch g r a n t s t o inc lude m i n o r i t i e s and women i n s tudy popula t ions so t h a t r e sea rch f ind ings can be of b e n e f i t t o a l l persons a t r i s k of t h e d i sease , d i s o r d e r o r cond i t ion under s tudy; s p e c i a l emphasis should be p laced on t h e need f o r i nc lus ion of m i n o r i t i e s and women i n s t u d i e s of d i s e a s e s , d i s o r d e r s and cond i t ions which d i sp ropor t iona te ly a f f e c t them. The composition of t h e proposed s tudy group must be descr ibed i n t e r m s of gender and r a c i a l l e t h n i c group. I n add i t ion , gender and r a c i a l l e t h n i c issues should be addressed i n developing a r e sea rch des ign and sample s ize appropr i a t e f o r t h e s c i e n t i f i c o b j e c t i v e s of t h e s tudy . This information should be included i n t h e form PHS 398 i n Sec t ion 2, A-D of t h e Research Plan and summarized i n Sec t ion 2, E , Human Sub jec t s , o r i n t h e program n a r r a t i v e s e c t i o n of Form PHS 5161 f o r S t a t e and l o c a l governments. If t h e r equ i r ed information is no t contained i n t h e a p p l i c a t i o n , t h e a p p l i c a t i o n w i l l be r e tu rned . A l l a p p l i c a t i o n s f o r r e sea rch submit ted t o AHCPR are requ i r ed t o address t h e s e p o l i c i e s . AHCPR w i l l n o t award g r a n t s t h a t do not comply with t h e s e p o l i c i e s . REVIEW PROCESS The acce le ra t ed review process involves t e c h n i c a l and s c i e n t i f i c review by Federal and/or non-Federal e x p e r t s s e rv ing as f i e ld r eade r s , r a t h e r t han a s tanding advisory committee. Sec t ion 922(d)(2) of t h e PHS A c t a l lows t h e Adminis t ra tor of AHCPR t o make adjustments i n t h e usua l peer review process f o r a p p l i c a t i o n s whose direct c o s t s do no t exceed $50,000. Small g r a n t proposa ls submit ted f o r r e sea rch on t o p i c s n o t s p e c i f i e d above, o r f o r r e sea rch conferences i n excess of $50,000, w i l l no t be accepted f o r expedi ted review, a l though they may be e l i g i b l e f o r t h e e s t a b l i s h e d AHCPR peer review process by a committee of non-Federal e x p e r t s . The f i n a l de te rmina t ion as t o whether an a p p l i c a t i o n q u a l i f i e s f o r expedi ted review is made by AHCPR, based on t h e a p p l i c a t i o n ' s cons is tency with t h e abovel i s ted p r i o r i t y areas. I f AHCPR determines t h a t an a p p l i c a t i o n intended by t h e a p p l i c a n t f o r expedi ted review is no t so q u a l i f i e d , t h e a p p l i c a t i o n w i l l be he ld f o r t h e next r e g u l a r a p p l i c a t i o n deadl ine f o r r o u t i n e g r a n t s r e c e i p t and peer review procedures. N I H GUIDE Vol. 20, No. 21, May 31, 1991 Page 13 ELIGIBLE APPLICANTS Appl ica t ions may be submitted by pub l i c o r p r i v a t e nonprof i t i n s t i t u t i o n s , u n i t s of S t a t e o r l o c a l government, o r i nd iv idua l s . APPLICATION PROCEDURES Applicat ions must be submitted i n accordance with Sec t ion 924 of t h e PHS A c t and with i n s t r u c t i o n s i n t h e a p p l i c a t i o n k i t and 42 CFR 67.13. \llUs/ APPLICATION FORMS A l l app l i can t s , except u n i t s of S t a t e and l o c a l governments, must use form PHS 398 ( r e v . 10/88). Applicants from S t a t e and l o c a l governments may use form PHS 5161, Applicat ion f o r Federal Ass is tance (nonconstruct ion programs). Grant a p p l i c a t i o n materials and i n s t r u c t i o n s are a v a i l a b l e from: Off ice of S c i e n t i f i c Review, Off ice of Planning and Resource Management, AHCPR, 5600 Fishe r s Lane, Room 18A-20, Rockvil le , Maryland 20857, te lephone (301) 443-3091. APPLICATION SUBMISSION To rece ive acce le ra t ed review, I t e m 2 of page 1 of t h e a p p l i c a t i o n should be checked '*Yes" and t h e PA number PA-91-62 and t h e t i t l e "AHCPR Small Grants Program" shouid be en te red . The o r i g i n a l and s i x copies of t h e a p p l i c a t i o n must be s e n t t o : Divis ion of Research Grants Nat ional I n s t i t u t e s of Health Westwood Building, Room 240 Bethesda, MD 20892** S t a t e and l o c a l governments us ing form DHHS 5161 must submit t h e o r i g i n a l and two copies of t h e completed a p p l i c a t i o n form t o t h e same l o c a t i o n . SUBMISSION DEADLINES The f i r s t deadl ine f o r r e c e i p t of p r i o r i t y and conference small g r a n t a p p l i c a t i o n s is September 15, 1991. Therea f t e r , t h e fol lowing dead l ines f o r r e c e i p t of a p p l i c a t i o n s are January 15, May 15, and September 15 f o r any yea r . Applicat ions w i l l be considered on t i m e i f they are rece ived on o r before t h e e s t a b l i s h e d deadl ine d a t e s o r s e n t on o r before t h e deadl ine d a t e s s p e c i f i e d i n t h i s Notice, un le s s t hey are rece ived t o o l a t e f o r o rde r ly process ing . Applicants should r eques t a l e g i b l y da ted U.S. Pos t a l Serv ice postmark o r ob ta in a dated r e c e i p t from a commercial carrier o r U.S. Pos t a l Serv ice . P r i v a t e metered postmarks s h a l l no t be acceptab le as proof of t imely mail ing. Late a p p l i c a t i o n s not accepted f o r processing w i l l be he ld f o r t h e next W r e g u l a r l y scheduled review cyc le . REVIEW CRITERIA Research g ran t a p p l i c a t i o n s w i l l be reviewed according t o t h e fol lowing c r i te r ia : ( 1 ) The s i g n i f i c a n c e and o r i g i n a l i t y from a s c i e n t i f i c o r t e c h n i c a l s tandpoin t of t h e goa l s of t h e p r o j e c t ; (2 ) t h e adequacy of t h e methodology proposed t o c a r r y out t h e p r o j e c t ; (3) t h e a v a i l a b i l i t y of d a t a o r t h e proposed p lan t o c o l l e c t d a t a r equ i r ed i n t h e a n a l y s i s ; ( 4 ) t h e adequacy and appropr ia teness of t h e p lan f o r organiz ing and ca r ry ing out t h e p r o j e c t ; (5) t h e q u a l i f i c a t i o n s of t h e P r i n c i p a l I n v e s t i g a t o r and t h e proposed s ta f f ; (6 ) t h e reasonableness of t h e proposed budget i n r e l a t i o n t o t h e proposed p r o j e c t ; ( 7 ) t h e adequacy of t h e f a c i l i t i e s and resources a v a i l a b l e t o t h e gran tee ; and ( 8 ) t h e adequacy of s t e p s proposed t o p r o t e c t human s u b j e c t s , as appropr i a t e . Conference g ran t a p p l i c a t i o n s w i l l be reviewed according t o t h e fol lowing add itiona l c r i te r ia : Signi f icance of t h e Proposed Conference: ( 1 ) The importance of t h e i s s u e o r problem addressed i n t h e d e l i v e r y , c o s t , q u a l i t y o f , o r access t o h e a l t h s e r v i c e s , o r a methodological o r t e c h n i c a l i s s u e i n dea l ing with t h e development and conduct of h e a l t h s e r v i c e s research; (2 ) t h e imp l i ca t ions of t h e conference 's intended outcome(s) f o r f u t u r e h e a l t h s e r v i c e s r e sea rch , f o r i d e n t i f y i n g o r r e so lv ing methodological problems, and f o r organiz ing and managing research a c t i v i t i e s ; and (3 ) t h e impl ica t ions of t h e conference f o r technologica l innovat ions i n h e a l t h care communications and d isseminat ion of knowledge, information, o r f o r t h e e f f e c t i v e u t i l i z a t i o n of t h e material communicated and disseminated. Conference Design: ( 1 ) The l o g i c and soundness of t h e conference 's conceptual framework; (2 ) t h e r o l e , composition, and e x p e r t i s e of i nd iv idua l s and advisory groups t o be u t i l i z e d i n planning or conducting t h e conference] inc luding t h e involvement of t h e p o t e n t i a l u s e r s of t h e information o r o t h e r products of t h e conference; ( 3 ) t h e reasonableness of t h e techniques proposed t o ensure maximum p a r t i c i p a t i o n and i n t e r a c t i o n among p a r t i c i p a n t s ] e . g . , t. d i scuss ion i n l a r g e and small groups, p r i o r d i s t r i b u t i o n of papers , pane ls versus ind iv idua l speakers , and per iods f o r ques t ions and answers; (4 ) t h e s p e c i f i c i t y of t h e proposed agenda of t o p i c s t o be addressed, t h e proposed N I H G U I D E Vol. 20, No. 21, May 31, 1991 Page 14 speakers and panel members f o r each t o p i c , t h e i r c r e d e n t i a l s , and t h e c r i t e r i a f o r t h e i r s e l e c t i o n ; and ( 5 ) t h e na tu re and q u a l i t y of t h e informat iona l products t o be disseminated as a r e s u l t of t h e conference (such as proceedings, r e sea rch agendas, pub l i ca t ions , t r a i n i n g manuals, and o t h e r products ) , and a plan f o r d i sseminat ion . Personnel and F a c i l i t i e s : (1) The experience and t r a i n i n g of t h e app l i can t i n d i c a t i n g t h e a b i l i t y t o des ign , organize, and c a r r y out a h e a l t h s e r v i c e s r e sea rch conference; and (2) t h e adequacy of t h e f a c i l i t i e s a v a i l a b l e f o r conducting t h e conference. Appropriateness of Budget: (1) The reasonableness of t h e o v e r a l l c o s t of t h e conference, given t h e proposed approach; and (2) t h e c o s t e f f e c t i v e n e s s of t h e t o t a l proposed expendi ture i n terms of t h e probable va lue of t h e conference r e s u l t s . FUNDING AVAILABILITY AHCPR expec ts t o award up to $1 m i l l i o n p e r yea r f o r a l l s m a l l g r a n t s . RELATED INFORMATION The AHCPR g r a n t program is descr ibed i n t h e Catalog of Federal Domestic Ass is tance as numbers 93.226 and 93.180. Appl ica t ions are not sub jec t t o Executive Order 12372. A l l g r a n t s funded under t h i s announcement are s u b j e c t t o g r a n t r e g u l a t i o n s set out i n 42 CFR P a r t 67, Subpart A , and t h e PHS Grants Pol icy Statement . For a d d i t i o n a l information on r e sea rch p r i o r i t y areas s p e c i f i e d i n t h i s n o t i c e , c o n t a c t : Center f o r General Heal th Se rv ices Extramural Research Agency f o r Heal th C a r e Pol icy and Research 2101 E a s t J e f f e r s o n S t r e e t , Room 678 Rockvi l le , MD 20852-4993 Telephone: (301) 443-2345 S p e c i f i c i nd iv idua l s f o r each area are as fo l lows (address is same as above): o Rural h e a l t h i s s u e s : Carole D . D i l l a r d Telephone: (301) 443-6990 o Minority h e a l t h i s s u e s : Frantz C . Wilson Telephone: (301) 443-2080 o Cost, access, and q u a l i t y of Fred J . He l l inge r , Ph.D. Telephone: (301) 443-6990 o HIVIAIDS i s s u e s : Melford Henderson Telephone: (301) 443-6990 o Medical l i a b i l i t y i s s u e s : Gary J. Young, J . D . care f o r t h e un insu redhnder insu red : N I H GUIDE Vol. 20, No. 21, May 31, 1991 Page 14 o C l i n i c a l Drac t ice-or ien ted primary care: Carolyn Clancy, M . D . Telephone: (301) 443-2080 For a d d i t i o n a l information on program a s p e c t s on conferences, con tac t : Margaret VanAmringe Direc to r , Center f o r Research Dissemination and Lia ison Agency f o r Heal th Care Pol icy and Research Parklawn Building, Room 18A-10 5600 Fishe r s Lane Rockvil le , MD 20857 Telephone: (301) 443-2904 For f i s ca l and admin i s t r a t ive matters, con tac t : N I H GUIDE Vol. 20, No. 21, May 31, 1991 Page 15 Ralph S l o a t Chief , Grants Management Branch Agency f o r Health Care Pol icy and Research Parklawn Building, Room 18A27 5600 F i she r s Lane Rockvil le , MD 20857 Telephone: (301) 443-4033 WrJ CUTANEOUS MANIFESTATIONS OF H I V INFECTION AND A I DS